Gene information
Official symbol PLAU
Official full name plasminogen activator, urokinase
Gene type protein-coding gene
Chromosome10q22.2
Alias symbolURK; UPA
Resources
Entrez Gene 5328
HGNC HGNC:9052
Ensembl ENSG00000122861
Vega OTTHUMG00000018494
UCSC uc001jwa.4
GO terms: 27 records
GO Description Category LogP Number of genes Detail
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0001952 regulation of cell-matrix adhesion GO Biological Processes -7.29794194 21 More
GO:0005925 focal adhesion GO Cellular Components -8.40302345 46 More
GO:0010469 regulation of signaling receptor activity GO Biological Processes -13.5880476 20 More
GO:0010757 negative regulation of plasminogen activation GO Biological Processes -7.90707903 5 More
GO:0010810 regulation of cell-substrate adhesion GO Biological Processes -12.3653476 37 More
GO:0014812 muscle cell migration GO Biological Processes -3.76678874 4 More
GO:0014910 regulation of smooth muscle cell migration GO Biological Processes -16.4082106 27 More
GO:0030055 cell-substrate junction GO Cellular Components -9.04790297 48 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0033628 regulation of cell adhesion mediated by integrin GO Biological Processes -4.66823778 6 More
GO:0035579 specific granule membrane GO Cellular Components -4.58725293 14 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0070821 tertiary granule membrane GO Cellular Components -3.64814241 11 More
GO:0098636 protein complex involved in cell adhesion GO Cellular Components -5.90313372 12 More
GO:0098637 protein complex involved in cell-matrix adhesion GO Cellular Components -3.72261873 5 More
GO:1904090 peptidase inhibitor complex GO Cellular Components -5.67855223 6 More
GO:1905286 serine-type peptidase complex GO Cellular Components -11.3739342 10 More
GO:1905370 serine-type endopeptidase complex GO Cellular Components -8.85311859 8 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
Drug-Gene interaction
view
Related drugs: 26 records
Drug name Interaction type Source PMID View
alendronic acid NCI 11984068 view
amediplase TTD view
antibiotic NCI 12724357 view
azacitidine NCI 10209960 view
bleomycin NCI 16224526 view
calcitriol NCI 3139763 view
carmustine NCI 9219734 view
celecoxib NCI 16172791 view
cisplatin NCI 9219734 view
clodronic acid NCI 11984068 view
dacarbazine NCI 9378540 view
estradiol NCI 9662256 view
filgrastim NCI 16331631 view
geldanamycin NCI 12724357 view
hydrocortisone NCI 2115769 view
ionomycin NCI 1701176 view
iressa NCI 16263158 view
papaverine NCI 16099300 view
razoxane NCI 9378540 view
retinol NCI 1576255 view
saruplase TTD view
sirolimus NCI 11245436 view
upamostat inhibitor TdgClinicalTrialTTD view
urokinase TdgClinicalTrialTTD 1282400112556741127454351257927112707394 view
verapamil NCI 9579573 view
zoledronic acid NCI 11984068 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_002658.6:c.*141C>T genomics myocardial infarction[diagnosis] myocardial infarction Xu J et al. Clin Sci (Lond). 2010
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